Proliferating cell nuclear antigen expression in mucoepidermoid carcinoma of salivary glands

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Proliferating cell nuclear antigen expression in mucoepidermoid carcinoma of salivary glands.

CONTEXT Among the cytological and morphological properties of mucoepidermoid carcinoma, one of the most important criteria for measuring its biological behavior and aggressiveness is cell proliferation. In this way, immunohistochemical markers of cell proliferation have been found to be useful in tumor classification and have formed part of the prognostic and therapeutic studies of these pathol...

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immunohistochemical analysis of e-cadherin expression in pleomorphic adenoma and mucoepidermoid carcinoma of salivary glands

objective: e-cadherin is a classic cadherin that plays a key role in epithelial cell adhesion. this protein is being referred to as the suppressor of proliferation and invasion. limited studies have investigated e-cadherin expression in salivary gland neoplasms. this study sought to assess the expression of e-cadherin and its possible role in progression and invasion of salivary gland neoplasms...

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study of myoepithelial cell markers in pleomorphic adenoma and mucoepidermoid carcinoma of salivary glands

introduction the application of immunohistochemical method has resulted in marked improvement of the microscopic diagnosis of neoplasms combined with h&e; staining. although unique cellular antigens have not been found in salivary gland neoplasms, multiple less specific immunomarkers have been used and may be helpful in elucidating the role of myoepithelial differentiation in those neoplasms. t...

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ژورنال

عنوان ژورنال: Sao Paulo Medical Journal

سال: 2000

ISSN: 1516-3180

DOI: 10.1590/s1516-31802000000300004